Introduction -- Physiologic changes during pregnancy -- Impact of pregnancy on maternal pharmacokinetics of medications -- Medications and the breastfeeding mother -- Fetal drug therapy -- Treating the placenta : an evolving therapeutic concept -- Conducting randomized controlled pharmaceutical trials in the pregnant population : challenges and solutions -- Pharmacogenomics in pregnancy -- Anesthetic drugs -- The management of asthma during pregnancy -- Nausea and vomiting of pregnancy -- Clinical pharmacology of anti-infectives during pregnancy -- Chemotherapy in pregnancy -- Substance abuse in pregnancy -- Diabetes in pregnancy -- Cardiovascular medications in pregnancy -- Antidepressants in pregnancy -- Uterotonics and tocolytics -- Antenatal thyroid disease and pharmacotherapy in pregnancy -- Management of dermatological conditions in pregnancy -- Herbs and alternative remedies -- Envenomations and antivenom during pregnancy -- Gastrointestinal disorders -- Challenges in predicting the pharmacokinetics of drugs in premature and mature newborns : example with piperacillin and tazobactam